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Most sedating antihistamine

The released histamine binds to its receptors (H-1 receptors) causing a chain reaction that includes an increase in blood flow to the area, and the release of other chemicals that add to the allergic response. Antihistamines work by blocking histamine receptors, therefore reducing the reactions that cause itching.

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It's stored in cells called mast cells, in almost all tissues of the body, and is released when the body reacts to a foreign substance (known as an allergen).More information about the potential side-effects associated with each specific medicine can be found in the patient information leaflet that will be provided with the medicine.It is important to tell your doctor or pharmacist what medicines you are taking, including those bought without a prescription and herbal medicines, before you start taking a new medicine.In addition, if you have liver or kidney disease you may need a lower dose of these medicines, though this depends on the particular medicine prescribed.Medicines that are not totally essential should ideally be avoided during pregnancy, and pregnant women should not take antihistamines unless prescribed by a doctor.These antihistamines will not be discussed further.) Antihistamines also may be used to treat motion sickness, insomnia (difficulty sleeping), and anxiety.

Antihistamines work by blocking the effects of a chemical called histamine that is responsible for many allergic symptoms.

The most commonly used ones are promethazine (Phenergan), hydroxyzine (Atarax), or alimemazine (Vallergan).

Non-sedating antihistamines such as cetirizine or loratadine are not effective at controlling the itch of eczema.

There might be a problem taking some herbal remedies and supplements alongside loratadine - especially ones that cause sleepiness, a dry mouth or make it difficult to pee.

Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue.

Antihistamines are medicines that can be used to relieve severe itching and help break this cycle.